| Players | Clubs | Position | Total | Goals | A |  |
 |
 |
Start | Sub | CO | Off | Pen S | Pen SV | Pen M | Pen C | OG | More |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gaston Ramirez | Sampdoria | Midfielder | 38 | 3 | 8 | 11 | 0 | 0 | 29 | 8 | 9 | 22 | 0 | 0 | 0 | 0 | 0 | |
| Luca Torreira | Sampdoria | Midfielder | 36 | 4 | 1 | 6 | 0 | 0 | 36 | 2 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | |
| Gianluca Caprari | Sampdoria | Midfielder | 35 | 5 | 1 | 5 | 1 | 0 | 20 | 17 | 15 | 13 | 0 | 0 | 0 | 0 | 0 | |
| Matias Silvestre | Sampdoria | Defender | 34 | 1 | 0 | 3 | 0 | 0 | 34 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | |
| Fabio Quagliarella | Sampdoria | Forward | 34 | 19 | 6 | 4 | 0 | 0 | 32 | 4 | 2 | 12 | 7 | 0 | 1 | 0 | 0 | |
| Dennis Praet | Sampdoria | Midfielder | 32 | 1 | 3 | 4 | 0 | 0 | 31 | 2 | 1 | 9 | 0 | 0 | 0 | 0 | 0 | |
| Bartosz Bereszynski | Sampdoria | Defender | 32 | 0 | 1 | 5 | 0 | 0 | 29 | 6 | 3 | 4 | 0 | 0 | 0 | 0 | 0 | |
| Duvan Zapata | Sampdoria | Forward | 31 | 11 | 3 | 1 | 0 | 0 | 24 | 9 | 7 | 11 | 0 | 0 | 0 | 0 | 0 | |
| Gianmarco Ferrari | Sampdoria | Defender | 29 | 2 | 0 | 4 | 0 | 0 | 28 | 10 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Edgar Barreto | Sampdoria | Midfielder | 29 | 1 | 0 | 5 | 1 | 0 | 25 | 8 | 4 | 10 | 0 | 0 | 0 | 0 | 0 | |
| Karol Linetty | Sampdoria | Midfielder | 28 | 3 | 2 | 7 | 0 | 0 | 20 | 13 | 8 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Emiliano Viviano | Sampdoria | Goalkeeper | 27 | 0 | 0 | 2 | 0 | 0 | 27 | 3 | 0 | 0 | 0 | 4 | 0 | 2 | 1 | |
| Dawid Kownacki | Sampdoria | Forward | 22 | 5 | 1 | 0 | 0 | 0 | 6 | 29 | 16 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Nicola Murru | Sampdoria | Defender | 20 | 0 | 2 | 4 | 0 | 0 | 16 | 16 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Valerio Verre | Sampdoria | Midfielder | 18 | 0 | 0 | 2 | 0 | 0 | 2 | 36 | 16 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Ivan Strinic | Sampdoria | Defender | 16 | 0 | 2 | 2 | 0 | 0 | 15 | 15 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | |
| Vasco Regini | Sampdoria | Defender | 14 | 0 | 0 | 2 | 0 | 0 | 11 | 27 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Jacopo Sala | Sampdoria | Midfielder | 12 | 0 | 0 | 1 | 0 | 1 | 11 | 22 | 1 | 4 | 0 | 0 | 0 | 0 | 0 | |
| Ricardo Alvarez | Sampdoria | Midfielder | 12 | 1 | 1 | 0 | 0 | 0 | 2 | 32 | 10 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Christian Puggioni | Sampdoria | Goalkeeper | 10 | 0 | 0 | 0 | 0 | 0 | 10 | 12 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | |
| Joachim Andersen | Sampdoria | Defender | 6 | 0 | 0 | 0 | 0 | 0 | 5 | 25 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Leonardo Capezzi | Sampdoria | Midfielder | 6 | 0 | 1 | 0 | 0 | 0 | 2 | 33 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Daniel Pavlovic | Sampdoria | Defender | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Vid Belec | Sampdoria | Goalkeeper | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 12 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
| Lorenco Simic | Sampdoria | Defender | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Filip Djuricic | Sampdoria | Midfielder | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 11 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Ognjen Stijepovic | Sampdoria | Midfielder | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Federico Bonazzoli | Sampdoria | Forward | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Dodo | Sampdoria | Defender | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Andrea Tessiore | Sampdoria | Midfielder | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Michal Tomic | Sampdoria | Midfielder | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Andrea Tozzo | Sampdoria | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 35 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Titas Krapikas | Sampdoria | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Gergely Hutvagner | Sampdoria | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A = Assists,
CS = Clean sheets Full
Sub = Started as a sub,
CO = Came on,
Off = Taken off,
S = Scored,
M = Missed,
Total = Total appearances,
OG = Own goals.