| 10 | Mohamed Salah | Group Stage | UEFA Champions League 17/18 |
| 10 | Sadio Mane | Group Stage | UEFA Champions League 17/18 |
| 10 | Roberto Firmino | Group Stage | UEFA Champions League 17/18 |
| 8 | Mohamed Salah | Group Stage | UEFA Champions League 22/23 |
| 8 | Mohamed Salah | Group Stage | UEFA Champions League 21/22 |
| 7 | Steven Gerrard | Group Stage | UEFA Champions League 08/09 |
| 6 | Mohamed Salah | Group Stage | UEFA Champions League 20/21 |
| 6 | Steven Gerrard | Group Stage | UEFA Champions League 07/08 |
| 6 | Fernando Torres | Group Stage | UEFA Champions League 07/08 |
| 6 | Peter Crouch | Group Stage | UEFA Champions League 06/07 |
| 5 | Sadio Mane | Group Stage | UEFA Champions League 21/22 |
| 5 | Roberto Firmino | Group Stage | UEFA Champions League 21/22 |
| 5 | Mohamed Salah | Group Stage | UEFA Champions League 18/19 |
| 5 | Philippe Coutinho | Group Stage | UEFA Champions League 17/18 |
| 5 | Dirk Kuyt | Group Stage | UEFA Champions League 07/08 |
| 5 | Ryan Babel | Group Stage | UEFA Champions League 07/08 |
| 5 | Luis Garcia | Round of 16 | UEFA Champions League 04/05 |
| 4 | Darwin Nunez | Group Stage | UEFA Champions League 22/23 |
| 4 | Diogo Jota | Group Stage | UEFA Champions League 20/21 |
| 4 | Mohamed Salah | Group Stage | UEFA Champions League 19/20 |
| 4 | Roberto Firmino | Group Stage | UEFA Champions League 18/19 |
| 4 | Sadio Mane | Group Stage | UEFA Champions League 18/19 |
| 4 | Michael Owen | First Group Stage | UEFA Champions League 02/03 |
| 3 | Sadio Mane | Group Stage | UEFA Champions League 20/21 |
| 3 | Alex Oxlade-Chamberlain | Group Stage | UEFA Champions League 19/20 |
| 3 | Divock Origi | Semi-finals | UEFA Champions League 18/19 |
| 3 | Peter Crouch | Group Stage | UEFA Champions League 07/08 |
| 3 | Yossi Benayoun | Group Stage | UEFA Champions League 07/08 |
| 3 | Luis Garcia | Group Stage | UEFA Champions League 06/07 |
| 3 | Steven Gerrard | Group Stage | UEFA Champions League 06/07 |
| 3 | Jari Litmanen | First Group Stage | UEFA Champions League 01/02 |
| 2 | Roberto Firmino | Group Stage | UEFA Champions League 22/23 |
| 2 | Harvey Elliott | Group Stage | UEFA Champions League 22/23 |
| 2 | Ibrahima Konate | Quarter-finals | UEFA Champions League 21/22 |
| 2 | Luis Diaz | Quarter-finals | UEFA Champions League 21/22 |
| 2 | Sadio Mane | Group Stage | UEFA Champions League 19/20 |
| 2 | Georginio Wijnaldum | Group Stage | UEFA Champions League 19/20 |
| 2 | Georginio Wijnaldum | Semi-finals | UEFA Champions League 18/19 |
| 2 | James Milner | Group Stage | UEFA Champions League 18/19 |
| 2 | Virgil van Dijk | Round of 16 | UEFA Champions League 18/19 |
| 2 | Alex Oxlade-Chamberlain | Group Stage | UEFA Champions League 17/18 |
| 2 | Steven Gerrard | Group Stage | UEFA Champions League 14/15 |
| 2 | Yossi Benayoun | Group Stage | UEFA Champions League 09/10 |
| 2 | Robbie Keane | Group Stage | UEFA Champions League 08/09 |
| 2 | Dirk Kuyt | Group Stage | UEFA Champions League 08/09 |
| 2 | Fernando Torres | Round of 16 | UEFA Champions League 08/09 |
| 2 | John Arne Riise | Round of 16 | UEFA Champions League 06/07 |
| 2 | Robbie Fowler | Group Stage | UEFA Champions League 06/07 |
| 2 | Luis Garcia | Group Stage | UEFA Champions League 05/06 |
| 2 | Djibril Cisse | Group Stage | UEFA Champions League 05/06 |
| 2 | Milan Baros | Group Stage | UEFA Champions League 04/05 |
| 2 | Steven Gerrard | Group Stage | UEFA Champions League 04/05 |
| 2 | Emile Heskey | First Group Stage | UEFA Champions League 02/03 |
| 2 | Michael Owen | First Group Stage | UEFA Champions League 01/02 |
| 2 | Danny Murphy | First Group Stage | UEFA Champions League 01/02 |
| 2 | Emile Heskey | Second Group Stage | UEFA Champions League 01/02 |
| 1 | Luis Diaz | Group Stage | UEFA Champions League 22/23 |
| 1 | Joel Matip | Group Stage | UEFA Champions League 22/23 |
| 1 | Trent Alexander-Arnold | Group Stage | UEFA Champions League 22/23 |
| 1 | Divock Origi | Group Stage | UEFA Champions League 21/22 |
