| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Juan Mata | 38 | 34 | 4 | 4 | 15 | 6 |
Chris Smalling | 35 | 35 | - | - | - | - |
Daley Blind | 35 | 35 | 2 | - | 3 | 1 |
David de Gea | 34 | 34 | - | - | - | - |
Anthony Martial | 31 | 29 | 2 | 2 | 2 | 11 |
Morgan Schneiderlin | 29 | 25 | 12 | 4 | 4 | 1 |
Memphis Depay | 29 | 16 | 21 | 13 | 6 | 2 |
Wayne Rooney | 28 | 27 | 1 | 1 | 4 | 8 |
Matteo Darmian | 28 | 24 | 7 | 4 | 11 | 1 |
Michael Carrick | 28 | 22 | 9 | 6 | 7 | - |
Ander Herrera | 27 | 17 | 15 | 10 | 11 | 3 |
Jesse Lingard | 25 | 19 | 6 | 6 | 8 | 4 |
Bastian Schweinsteiger | 18 | 13 | 5 | 5 | 5 | 1 |
Marouane Fellaini | 18 | 12 | 15 | 6 | 6 | 1 |
Ashley Young | 18 | 11 | 14 | 7 | 3 | 1 |
Marcos Rojo | 16 | 15 | 3 | 1 | 6 | - |
Luis Antonio Valencia | 14 | 8 | 10 | 6 | 2 | - |
Marcus Rashford | 11 | 11 | 2 | - | 7 | 5 |
Cameron Borthwick-Jackson | 10 | 6 | 10 | 4 | 1 | - |
Phil Jones | 10 | 6 | 7 | 4 | 2 | - |
Paddy McNair | 8 | 3 | 20 | 5 | 2 | - |
Timothy Fosu-Mensah | 8 | 2 | 8 | 6 | 1 | - |
Luke Shaw | 5 | 5 | - | - | - | - |
Adnan Januzaj | 5 | 2 | 5 | 3 | 2 | 1 |
Sergio Romero | 4 | 4 | 33 | - | - | - |
Guillermo Varela | 4 | 3 | 9 | 1 | - | - |
Andreas Pereira | 4 | - | 21 | 4 | - | - |
Javier Hernandez | 1 | - | 4 | 1 | - | - |
Nick Powell | 1 | - | 1 | 1 | - | - |
James Wilson | 1 | - | 1 | 1 | - | - |
Will Keane | 1 | - | 1 | 1 | - | - |
James Weir | 1 | - | 5 | 1 | - | - |
Donald Love | 1 | - | 1 | 1 | - | - |
Joe Riley | - | - | 2 | - | - | - |
Axel Tuanzebe | - | - | 2 | - | - | - |
Sam Johnstone | - | - | 5 | - | - | - |
Sean Goss | - | - | 1 | - | - | - |
Joe Rothwell | - | - | 1 | - | - | - | 526 | 418 | 265 | 108 | 108 | 46 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .