| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Jorge Koke | 36 | 36 | - | - | 2 | 4 |
Antoine Griezmann | 36 | 36 | 1 | - | 14 | 16 |
Filipe Luis | 34 | 34 | - | - | 3 | 3 |
Fernandez Gabi | 34 | 33 | 2 | 1 | 6 | - |
Yannick Carrasco | 34 | 26 | 9 | 8 | 20 | 10 |
Saul Niguez | 33 | 29 | 6 | 4 | 6 | 4 |
Stefan Savic | 32 | 30 | 6 | 2 | - | 1 |
Angel Correa | 32 | 11 | 26 | 21 | 7 | 4 |
Diego Godin | 31 | 30 | 1 | 1 | - | 3 |
Kevin Gameiro | 31 | 21 | 12 | 10 | 18 | 12 |
Fernando Torres | 31 | 13 | 21 | 18 | 11 | 8 |
Jan Oblak | 30 | 30 | - | - | 1 | - |
Juanfran | 23 | 21 | 8 | 2 | 1 | - |
Nicolas Gaitan | 23 | 11 | 23 | 12 | 7 | 3 |
Jose Maria Gimenez | 17 | 12 | 17 | 5 | 3 | - |
Thomas Partey | 16 | 6 | 19 | 10 | 2 | 1 |
Lucas Hernandez | 15 | 13 | 21 | 2 | - | - |
Sime Vrsaljko | 14 | 11 | 13 | 3 | 2 | - |
Tiago | 12 | 5 | 13 | 7 | 4 | 1 |
Miguel Angel Moya | 8 | 7 | 11 | 1 | - | - |
Augusto Fernandez | 3 | 2 | 2 | 1 | 2 | - |
Antonio Moya | 1 | 1 | 5 | - | - | - |
Alessio Cerci | 1 | - | 8 | 1 | - | - |
Bernabe Barragan | - | - | 2 | - | - | - |
Keidi Bare | - | - | 4 | - | - | - |
Caio Henrique | - | - | 2 | - | - | - |
Nicolas Schiappacasse | - | - | 1 | - | - | - |
Roberto Nunez | - | - | 1 | - | - | - |
Alex Garcia | - | - | 1 | - | - | - |
Andre Moreira | - | - | 21 | - | - | - |
Juan Moreno | - | - | 5 | - | - | - |
Roberto Olabe | - | - | 1 | - | - | - |
Mohammed Zakaria | - | - | 1 | - | - | - |
Rafael Munoz | - | - | 1 | - | - | - | 527 | 418 | 264 | 109 | 109 | 70 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .